Thermo Scientific Chemicals L(-)-Proline, 99+%

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• L-Proline is an amino acid that is found as a component of various proteins.

Application
• L-Proline is used as asymmetric catalyst in organic synthesis and asymmetric aldol cyclization
• It is also used along with ninhydrin in chromatography
• It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes
• It is used in pharmaceutical and biotechnological applications due to its osmoprotactant property
• It is precursor of hydroxyproline in collage and involved in proper functioning of joint and tendons

Chemical Identifiers

• CAS: 147-85-3
• Molecular Weight (g/mol): 115.13
• InChI Key: ONIBWKKTOPOVIA-UHFFFAOYNA-N
• PubChem CID: 145742
• SMILES: OC(=O)C1CCCN1

• Molecular Formula: C5H9NO2
• MDL Number: MFCD00064318
• Synonym: l-proline, proline, l---proline, s-pyrrolidine-2-carboxylic acid, 2-pyrrolidinecarboxylic acid, --proline, --s-proline, 2s-pyrrolidine-2-carboxylic acid, prolinum, h-pro-oh
• ChEBI: CHEBI:17203

Specifications

• Ammonium: 200ppm max.
• Arsenic (As): 1ppm max.
• Color: White
• Heavy Metals (as Pb): 10ppm max.
• Iron (Fe): 10ppm max.
• Loss on Drying: 0.3% max. (105°C, 3 hrs)
• Molecular Formula: C5H9NO2
• Beilstein: 22, 2
• Fieser: 06,492; 08,421; 09,393; 10,331; 11,446; 13,292
• Merck Index: 15, 7895
• Sulfated Ash: 0.1% max.
• InChI Key: ONIBWKKTOPOVIA-UHFFFAOYNA-N
• SMILES: OC(=O)C1CCCN1
• Specific Rotation Condition: − 85.50 (20.00°C c=4,H2O)
• PubChem CID: 145742
• Formula Weight: 115.13
• Physical Form: Crystalline Powder or Crystals

• CAS: 147-85-3
• pH: 5.5 to 7 (2.5% soln. at 25°C)
• Chlorine (Cl): 200ppm max.
• Infrared Spectrum: Authentic
• Assay Percent Range: 99+%
• Other Amino Acids: 0.5% max. (TLC)
• MDL Number: MFCD00064318
• Specific Rotation: -84.5° to -86.8° (20°C, 589nm) (c=4, H2O)
• Sulfate: 200ppm max.
• Transmittance: 95% min. (c=10, H2O, 430nm) 1cm cell
• Synonym: l-proline, proline, l---proline, s-pyrrolidine-2-carboxylic acid, 2-pyrrolidinecarboxylic acid, --proline, --s-proline, 2s-pyrrolidine-2-carboxylic acid, prolinum, h-pro-oh
• Density: 1.3500g/mL
• IUPAC Name: (2S)-pyrrolidine-2-carboxylic acid
• Molecular Weight (g/mol): 115.13
• ChEBI: CHEBI:17203
• Percent Purity: 99.0 to 101.0%
• Chemical Name or Material: L(-)-Proline

RUO – Research Use Only