L-Proline, 99%, Thermo Scientific Chemicals

Description

L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It is a precursor of hydroxyproline in collagen. It is an active component of collagen and involved in the proper functioning of joints and tendons. It finds uses in pharmaceutical, biotechnological applications due to its osmoprotectant property. Further, it is used with ninhydrin in the chromatography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It is a precursor of hydroxyproline in

Specifications

Chemical Identifiers

• CAS: 147-85-3
• Molecular Formula: C5H9NO2
• Molecular Weight (g/mol): 115.13
• MDL Number: MFCD00064318
• InChI Key: ONIBWKKTOPOVIA-UHFFFAOYNA-N
• Synonym: l-proline, proline, l---proline, s-pyrrolidine-2-carboxylic acid, 2-pyrrolidinecarboxylic acid, --proline, --s-proline, 2s-pyrrolidine-2-carboxylic acid, prolinum, h-pro-oh
• PubChem CID: 145742
• ChEBI: CHEBI:17203
• IUPAC Name: (2S)-pyrrolidine-2-carboxylic acid
• SMILES: OC(=O)C1CCCN1

• Melting Point: ∼225°C (decomposition)
• Beilstein: 80810
• Merck Index: 14,7780
• Solubility Information: Soluble in water and ethanol. Insoluble in ether,butanol and isopropanol.
• Density: 1.36
• Quantity: 500 g
• Formula Weight: 115.13
• Optical Rotation: −84° (c=1 in water)
• Sensitivity: Hygroscopic
• Percent Purity: 99%
• Chemical Name or Material: L-Proline

RUO – Research Use Only