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Epredia™ Lab Vision™ Vinculin Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide
Provide accurate, reproducible results with the Epredia™ Vinculin Ab-1, Mouse Monoclonal Antibody.
Brand: Epredia™ MS-1209-P
Description
Vinculin is an attachment protein involved in the indirect binding of intracellular actin filaments to extracellular fibronectin. Vinculin binds to actin capping protein and α actinin, which in turn binds to actin. The binding of fibronectin is also indirect where vinculin binds to talin, which in turn binds to the intracellular domain of the fibronectin receptor which itself is the ligand for fibronectin. Vinculin is widely distributed in tissue and is expressed where smooth muscle actin and fibroblasts attach to the extracellular matrix.Host Species: Mouse
Clone: VLN01
Isotype: IgG
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Semi-purified vinculin
Molecular Weight: 130kDa (vinculin) and 150kDa (meta-vinculin)
Positive Control: HeLa cells, skin
Cellular Localization: Cell membrane and cytoplasmic Ab-1 is useful for studies of vinculin in platelet activation.
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Immunoprecipitation (Denatured verified)
Note:
USA: RUO; Int'l: RUO
Specifications
Vinculin Ab-1 | |
Monoclonal | |
200μg/mL | |
Mouse | |
1 mL | |
Cytoskeletal Protein | |
Human | |
IgG |
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
VLN01 | |
Unconjugated | |
Semi-purified vinculin | |
RUO | |
Primary | |
Concentrated |