Invitrogen™ LanthaScreen™ Tb-peIF2a (pSer52) Antibody

The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis.

Marke:  Invitrogen™ PV4815

Artikelnummer. 10013574

Beschreibung

The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis. In response to a cellular stress, phosphorylation of eIF2alpha at Ser52 occurs by the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2) to prohibit the initiation of protein synthesis.

For use in combination with the GFP-EIF2alpha physiological protein substrate (Cat. No. PV4809) to evaluate inhibitors in medium to high throughput screening applications.

Spezifikation

• Antigen: Serine/threonine kinase
• Concentration: 0.47 mg/mL
• Quantity: 25 μg
• Research Discipline: Pharma and Biopharma
• Packaging: 1 Each
• Form: Liquid
• Reactivity: Human
• Readout: End Point
• Target Gene: Ser/Thr Kinases

• Applications: Kinase Assay
• Conjugate: Tb (Terbium)/Lanthanide Chelates
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Terbium-labeled peIF2a (pThr46) antibody in HEPES buffered saline. Store at -20°C.
• Excitation/Emission: 340/490, 520 nm
• Shipping Condition: Dry Ice
• Reactivity abrv: Hu
• Product Line: LanthaScreen™

For Research Use Only. Not for use in diagnostic procedures.