Latrunculin B, Tocris Bioscience™

Description

Inhibitor of actin polymerization

Inhibitor of actin polymerization. Interacts with G-actin in a 1:1 ratio to inhibit polymerization into F-actin in vitro (IC50 values are ∽60 and ∽900 nM in absence and presence of calf serum, respectively). Marine toxin.

Specifications

• CAS: 76343-94-7
• Molecular Formula: C20H29NO5S
• Linear Formula: C₂₀H₂₉NO₅S
• MDL Number: MFCD00270879
• Quantity: 1 mg
• Synonym: latrunculin b, lat-b, unii-lw7u308u7u, latrunculin b, latrunculia magnifica, 4r-4-1r,4s,5z,9z,13r,15r-15-hydroxy-4,9-dimethyl-11-oxo-12,16-dioxabicyclo 11.3.1 heptadeca-5,9-dien-15-yl-1,3-thiazolidin-2-one, lat b, +-latrunculin b, d07ehb, latrunculin b from latruncula magnifica, 2-thiazolidinone, 4-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo 11.3.1 heptadeca-4,8-dien-15-yl-, 1r*,4z,8z,10s*,13r*,15r* r*-+
• Solubility Information: Soluble to 50mM in DMSO and to 50mM in ethanol
• InChI Key: NSHPHXHGRHSMIK-JRIKCGFMSA-N
• SMILES: C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]2CSC(=O)N2)OC(=O)\C=C(C)/CC\C=C/1
• IUPAC Name: (4R)-4-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-1,3-thiazolidin-2-one
• Molecular Weight (g/mol): 395.51
• PubChem CID: 6436219
• ChEBI: CHEBI:49703
• Formula Weight: 395.51
• Percent Purity: 0.95
• Physical Form: Lyophilized Film
• Chemical Name or Material: (4R)-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-d
• Grade: >97%