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Eurofins DiscoverX LATS2 Protein, Active
Active, N-Terminal GST-tagged, recombinant, human LATS2, amino acid residues 553-end and N-Terminal 6His-tagged, recombinant, human MOBKL1A, full length, for use in Kinase Assays.
£448.44 - £3422.71
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
|---|---|
| Molecular Weight (g/mol) | 89 kDa (LATS2) and 30 kDa (MOBKL1A) |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal GST / N-terminal 6His |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17300884
|
Eurofins DiscoverX
14-987 |
10 μg |
£448.44
10µg |
Estimated Shipment: 16-09-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
17310884
|
Eurofins DiscoverX
14-987M |
250 μg |
£3422.71
250µg |
Estimated Shipment: 16-09-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
GenBank NM_014572.2 / GenBank BC038112
Specifications
| mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. | |
| Human | |
| N-terminal GST / N-terminal 6His | |
| Truncated | |
| LATS2, active |
| 89 kDa (LATS2) and 30 kDa (MOBKL1A) | |
| Recombinant | |
| Recombinant enzyme expressed in Sf21 insect cells | |
| Combined ≥52% |