Luteolin, Tocris Bioscience™

Description

Anti-inflammatory, antioxidant and free radical scavenger

Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 activation. Also inhibits TNF-α -induced COX-2 expression. Antiproliferative and chemopreventative; inhibits proliferation of Lewis lung carcinoma cells in vivo. Inhibits influenza virus replication in vitro by preventing viral entry. Molecular docking studies also indicate binding to SARS-CoV-2 main protease (Mpro or 3CLpro).

Specifications

Chemical Identifiers

• CAS: 491-70-3
• Molecular Formula: C15H10O6
• Molecular Weight (g/mol): 286.239
• InChI Key: IQPNAANSBPBGFQ-UHFFFAOYSA-N
• Synonym: luteolin, 3',4',5,7-tetrahydroxyflavone, 2-3,4-dihydroxyphenyl-5,7-dihydroxy-4h-chromen-4-one, digitoflavone, luteolol, flacitran, luteoline, weld lake, cyanidenon 1470, salifazide
• PubChem CID: 5280445
• ChEBI: CHEBI:15864
• IUPAC Name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
• SMILES: C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O

• Quantity: 10 mg
• Formula Weight: 286.24
• Percent Purity: >98%
• Chemical Name or Material: Luteolin