Luzindole, 97%, Thermo Scientific Chemicals

Description

A melatonin receptor antagonist

Luzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Luzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response

Solubility
Soluble in DMSO (100 mM), ethanol (100 mM), chloroform, methanol, and water.

Notes
Protect from heat. Incompatible with heat and oxidizing agents. Store at 4°C.

Specifications

Chemical Identifiers

• CAS: 117946-91-5
• Molecular Formula: C19H20N2O
• Molecular Weight (g/mol): 292.38
• MDL Number: MFCD00672498
• InChI Key: WVVXBPKOIZGVNS-UHFFFAOYSA-N
• Synonym: luzindole, n-acetyl-2-benzyltryptamine, 2-benzyl-n-acetyltryptamine, n-2-2-benzyl-1h-indol-3-yl ethyl acetamide, n-2-2-phenylmethyl-1h-indol-3-yl ethyl acetamide, tocris-0877, n-acetyl-2-benzyl-tryptamine, acetamide, n-2-2-phenylmethyl-1h-indol-3-yl ethyl, n-2-2-benzylindol-3-yl ethyl acetamide
• PubChem CID: 122162
• IUPAC Name: N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide
• SMILES: CC(=O)NCCC1=C(CC2=CC=CC=C2)NC2=CC=CC=C12

• Melting Point: 44°C to 46°C
• Color: White to Brown
• Quantity: 5 mg
• Solubility Information: Soluble in DMSO (100 mM),ethanol (100 mM),chloroform,methanol,and water.
• Formula Weight: 292.37
• Percent Purity: 97%
• Physical Form: Powder
• Chemical Name or Material: Luzindole

RUO – Research Use Only