LY 272015 hydrochloride, Tocris Bioscience™

Description

High affinity 5-HT2B antagonist; orally active

High affinity 5-HT2B receptor antagonist that displays selectivity over 5-HT2A and 5-HT2C receptors (Ki values are 0.75, 21.63 and 28.7 nM for 5-HT2B, 5-HT2C and 5-HT2A receptors respectively). Orally active.

Specifications

Chemical Identifiers

• CAS: 172895-15-7
• Molecular Formula: C21H25ClN2O2
• Molecular Weight (g/mol): 372.893
• InChI Key: BKAZOTIBKRWLQA-UHFFFAOYSA-N
• Synonym: ly 272015 hydrochloride, 1-3,4-dimethoxybenzyl-6-methyl-2,3,4,9-tetrahydro-1h-pyrido 3,4-b indole hcl, 1-3,4-dimethoxyphenyl methy-2,3,4,9-tetrahydro-6-methyl-1h-pyrido 3,4-b indole hydrochloride, 1-3,4-dimethoxyphenyl methyl-6-methyl-1h,2h,3h,4h,9h-pyrido 3,4-b indole hydrochloride
• PubChem CID: 9929423
• IUPAC Name: 1-[(3,4-dimethoxyphenyl)methyl]-6-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole;hydrochloride
• SMILES: CC1=CC2=C(C=C1)NC3=C2CCNC3CC4=CC(=C(C=C4)OC)OC.Cl

• Quantity: 10 mg
• Formula Weight: 372.89
• Percent Purity: >99%
• Chemical Name or Material: LY 272015 hydrochloride