LY 354740, Tocris Bioscience™

Description

Potent and highly selective group II mGlu agonist

Highly selective and potent agonist of group II mGlu receptors (EC50 values are 5.1 and 24.3 nM at mGlu2 and mGlu3 receptors respectively and > 100000 nM at mGlu4, mGlu7, mGlu1a and mGlu5a receptors). Displays antianxiety and antiaddictive activity in vivo. Orally and systemically active.

Specifications

Chemical Identifiers

• CAS: 176199-48-7
• Molecular Formula: C8H11NO4
• Molecular Weight (g/mol): 185.18
• MDL Number: MFCD04113018
• InChI Key: VTAARTQTOOYTES-RGDLXGNYSA-N
• Synonym: eglumegad, eglumetad, 1s,2s,5r,6s-2-aminobicyclo 3.1.0 hexane-2,6-dicarboxylic acid, eglumegad inn, unii-onu5a67t2s, 3h eglumegad, chembl8759, onu5a67t2s, eglumegad usan
• PubChem CID: 213056
• IUPAC Name: (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
• SMILES: N[C@]1(CC[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O

• Quantity: 10 mg
• Formula Weight: 185.18
• Percent Purity: >98%
• Chemical Name or Material: LY 354740