LY 367385, Tocris Bioscience™

Description

Selective mGlu1a antagonist

A selective mGlu1a receptor antagonist, with an IC50 value of 8.8 μM for blockade of quisqualate-induced phosphoinositide hydrolysis vs. > 100 μM for mGlu5a, and negligible action on group II and III receptors.

Specifications

Chemical Identifiers

• CAS: 198419-91-9
• Molecular Formula: C10H11NO4
• Molecular Weight (g/mol): 209.201
• InChI Key: SGIKDIUCJAUSRD-QMMMGPOBSA-N
• Synonym: unii-d8uw47h17b, ly-367385 hydrochloride, chembl94631, 4-s-amino carboxy methyl-3-methylbenzoic acid, s-+-a-amino-4-carboxy-2-methylbenzeneacetic acid, 4-1s-1-amino-2-hydroxy-2-oxoethyl-3-methylbenzoic acid, tocris-1237, d04jqr, l-367385 analogs, lilly, metabotropic mglur1 agonists, lilly
• PubChem CID: 5311261
• IUPAC Name: 4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid
• SMILES: CC1=C(C=CC(=C1)C(=O)O)C(C(=O)O)N

• Quantity: 10 mg
• Formula Weight: 209.2
• Percent Purity: >99%
• Chemical Name or Material: LY 367385