Cytiva MabSelect™ Chromatography Media

Protein A affinity medium designed for capturing MAbs from large sample volumes

Product Code	Brand	Quantity
11339981	Cytiva 17-5199-01	25 mL
11359981	Cytiva 17-5199-02	200 mL

Description

• High-flow agarose matrix allows for high flow velocities at production scale
• BioProcess medium supported for industrial applications and well-established in approved processes
• Low non-specific binding resulting in low levels of impurities in the product eluate pool
• Oriented coupling of ligand and optimized matrix gives high dynamic binding capacity
• Based on highly cross-linked agarose matrix with recombinant protein A ligand
• Ligand is engineered to favor oriented coupling and expressed in E. coli and is free of components of mammalian origin
• Hydrophilic nature of the base matrix ensures low levels of non-specific

• Average particle size: 85μm (d50V)
• pH Stability cleaning-in-place (CIP): 2 to 12
• pH Stability working range: 3 to 10
• Ligand: recombinant protein A (E.coli)
• Matrix: highly cross-linked agarose
• Binding capacity/mL chromatography medium: ∽30mg human lgG/mL at 2.4 min. residence time
• Pressure/Flow specification: <500cm/hr., <200 kPa, BPG 300, bed height 20cm

Specifications

• For Use With (Application): For Industrial AppliCatIons and Well-Established in Approved Processes
• Binding Capacity: 30 mg Human lgG/mL (at 2.4 min. residence time)
• Flow Rate: <500 cm/Hoμr
• Height (English) Bed: 7.87 in.
• Includes: Certificate of Analysis
• Matrix: Highly Cross-Linked Agarose
• Ligand Type: Recombinant Protein A (E. coli)

• Storage Requirements: 2°C to 8°C
• Product Type: MabSelect Media
• Particle Size: 85 μm
• Height (Metric) Bed: 20 cm
• Max. Pressure: <200 kPa
• pH Range: 3 to 10

Safety and Handling

Product Identifier

• MabSelect, 25 ml

Signal Word

• Warning

Hazard Category

• Flammable liquid Category 3

Hazard Statement

• H226-Flammable liquid and vapour.

Precautionary Statement

• P241-Use explosion-proof electrical/ventilating/lighting/ equipment.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : ethanol
• UNKNOWN ACUTE-16.5 per cent of the mixture consists of component(s) of unknown acute toxicity.