Malononitrile, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11408840	Thermo Scientific Alfa Aesar A15046.06	5 g
11467307	Thermo Scientific Alfa Aesar A15046.22	100 g
11477307	Thermo Scientific Alfa Aesar A15046.36	500 g
11487307	Thermo Scientific Alfa Aesar A15046.0E	2500 g

Description

Crosslinking agent for modification of proteins via amidationMalononitrile is used as a precursor in the preparation of anti-cancer drug, triamterene, adenine, methotrexate, thiamine, acrylic fibers and dyes. It is used in Knoevenagel condensation to prepare 2-chlorobenzalmalononitrile by reacting with 2-chlorobenzaldehyde. It acts as a leaching agent for gold. It is used as a raw material for the Gewald reaction of ketone or aldehyde to produce 2-aminothiophene using elemental sulfur and a base. Further, it plays an important role in the preparation of [1,6]-naphthyridines, gamma-ketoamides, 1,4-dihydropyridine, chromeno[2,3-b]pyridine and dihydro-1,4-dithiepine frameworks.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Crosslinking agent for modification of proteins via amidationMalononitrile is used as a precursor in the preparation of anti-cancer drug, triamterene, adenine, methotrexate, thiamine, acrylic fibers and dyes. It is used in Knoevenagel condensation to prepare 2-chlorobenzalmalononitrile by reacting with 2-chlorobenzaldehyde. It acts as a leaching agent for gold. It is used as a raw material for the Gewald reaction of ketone or aldehyde to produce 2-aminothiophene using elemental sulfur and a base. Further, it plays an important role in the preparation of [1,6]-naphthyridines, gamma-ketoamides, 1,4-dihydropyridine, chromeno[2,3-b]pyridine and dihydro-1,4-dithiepine frameworks.

Solubility
Soluble in water, acetone, acetic acid, chloroform, ethanol, ether and benzene.

Notes
Store in a cool place. Incompatible with strong oxidizing agents, strong reducing agents, strong acids and strong bases.

Chemical Identifiers

• CAS: 109-77-3
• MDL Number: MFCD00001883
• Synonym: malononitrile, dicyanomethane, cyanoacetonitrile, malonic dinitrile, methylene cyanide, dicyanmethane, malonodinitrile, malonic acid dinitrile, methylenedinitrile, methane, dicyano
• ChEBI: CHEBI:33186

• Molecular Formula: C3H2N2
• InChI Key: CUONGYYJJVDODC-UHFFFAOYSA-N
• PubChem CID: 8010
• IUPAC Name: propanedinitrile

Specifications

• CAS: 109-77-3
• Density: 1.049
• Flash Point: 112°C
• Refractive Index: 1.415
• UN Number: UN2647
• Merck Index: 14,5711
• Solubility Information: Soluble aq. soln.,acetone,acetic acid,chloroform,ethanol,ether and benzene.
• SMILES: N#CCC#N
• Molecular Weight (g/mol): 66.06
• ChEBI: CHEBI:33186
• Percent Purity: 99%

• Melting Point: 30°C to 34°C
• Boiling Point: 220°C to 222°C
• Molecular Formula: C3H2N2
• MDL Number: MFCD00001883
• Beilstein: 773697
• Synonym: malononitrile, dicyanomethane, cyanoacetonitrile, malonic dinitrile, methylene cyanide, dicyanmethane, malonodinitrile, malonic acid dinitrile, methylenedinitrile, methane, dicyano
• InChI Key: CUONGYYJJVDODC-UHFFFAOYSA-N
• IUPAC Name: propanedinitrile
• PubChem CID: 8010
• Formula Weight: 66.06
• Chemical Name or Material: Malononitrile

Safety and Handling

GHS H Statement

H301-H311-H331

Toxic if swallowed.

Toxic in contact with skin.

Toxic if inhaled.

P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P311-P312-P330-P361-P363-P501c

H301+H311+H331

missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: MALONONITRILE

missing translation for 'einecsNumber' : 203-703-2

missing translation for 'rtecsNumber' : OO3150000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only