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MAP2 Monoclonal Antibody (AP18), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA512826

Product Code. 11344723

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Description

Description

MA5-12826 has been successfully used in immunofluorescence analysis of Map2 in human glutamate neurons derived from iPSCs.

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).
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Product Title
MAP2 Monoclonal Antibody (AP18), Invitrogen™ > 500 μL; Unconjugated

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