Marimastat, Tocris Bioscience™

Description

Broad spectrum MMP inhibitor

Broad spectrum inhibitor of MMPs (IC50 values are 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively). Inhibits peritoneal dissemination of human gastric cancer cells in vivo through inhibition of tumor angiogenesis.

Specifications

Chemical Identifiers

• CAS: 154039-60-8
• Molecular Formula: C15H29N3O5
• Molecular Weight (g/mol): 331.413
• InChI Key: OCSMOTCMPXTDND-OUAUKWLOSA-N
• Synonym: marimastat, marimastat usan, marimastat usan/inn, unii-d5eqv23tds, d5eqv23tds, 2s,3r-3-1s-2,2-dimethyl-1-methylcarbamoxy propyl carboyl-2-hydroxy-5-methylhexanohydroxamic acid, 2s,3r-3-1s-2,2-dimethyl-1-methylcarbamoyl propyl carbamoyl-2-hydroxy-5-methylhexanohydroxamic acid, 2s,3r-n 4-2s-3,3-dimethyl-1-methylamino-1-oxobutan-2-yl-n 1 ,2-dihydroxy-3-2-methylpropyl butanediamide, 2r,3s-n-2s-3,3-dimethyl-1-methylamino-1-oxobutan-2-yl-n',3-dihydroxy-2-2-methylpropyl butanediamide, 2s,3r-n-1s-2,2-dimethyl-1-methylcarbamoyl propyl-n',2-dihydroxy-3-2-methylpropyl butanediamide
• PubChem CID: 119031
• ChEBI: CHEBI:50662
• IUPAC Name: (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N',3-dihydroxy-2-(2-methylpropyl)butanediamide
• SMILES: CC(C)CC(C(C(=O)NO)O)C(=O)NC(C(=O)NC)C(C)(C)C

• Quantity: 1 mg
• Formula Weight: 331.41
• Percent Purity: >99%
• Chemical Name or Material: Marimastat