Megestrol Acetate, Tocris Bioscience™

Description

Synthetic progesterone analog

Synthetic progesterone analog. Dose-dependently inhibits growth of HepG2 cells (IC50 = 260 μM) in vitro and in vivo and reduces tumor volume. High dosages improve weight gain in tumor-bearing nude mice. Orally bioavailable.

Specifications

• CAS: 595-33-5
• Molecular Formula: C24H32O4
• Linear Formula: C₂₄H₃₂O₄
• Quantity: 50 mg
• Synonym: megestrol acetate, niagestin, megace es, megestryl acetate, megace, megeron, ovaban, ovarid, pallace, magestin
• Solubility Information: Soluble to 50mM in DMSO and to 20mM in ethanol
• InChI Key: RQZAXGRLVPAYTJ-GQFGMJRRSA-N
• SMILES: CC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C
• IUPAC Name: [(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
• Molecular Weight (g/mol): 384.516
• PubChem CID: 11683
• Formula Weight: 384.51
• Percent Purity: >98%
• Physical Form: Solid
• Chemical Name or Material: 17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione