Thermo Scientific Chemicals Melatonine, 99%

Description

Melatonine, 99%, CAS # 73-31-4, is a hormone usually produced in the pineal gland and released into the blood.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Melatonine is a hormone produced by the pineal gland that shows several biological activities, including the somnolence, sleep-wake cycle, circadian rhythm, stress response, aging, and immunity activities

• It shows antioxidant, autocoid, paracoid, hormonal, anti- inflammatory and anti-apoptotic activities

Applications

• Melatonin shows neurohormonal activity and can upregulate antioxidant enzymes and inhibit rat NOS1

• Melatonin has been reported to be an activator of MEL-1A-R and MEL-1B-R

• The production and secretion of melatonine are dependent on beta-adrenergic receptor function

• During melatonine synthesis, the essential amino acid L-tryptophan is used as a precursor

• This compound inhibits apoptosis in immune cells and neurons, and enhances apoptotic cell death of cancer cells

• It can inhibit proliferation and metastasis of breast cancer cells by modulating Rho-associated kinase protein-1 expression

Specifications

Chemical Identifiers

• CAS: 73-31-4
• Molecular Formula: C₁₃H₁₆N₂O₂
• Molecular Weight (g/mol): 232.28
• MDL Number: MFCD00005655
• InChI Key: DRLFMBDRBRZALE-UHFFFAOYSA-N
• Synonym: melatonin, melatonine, n-acetyl-5-methoxytryptamine, circadin, 5-methoxy-n-acetyltryptamine, n-2-5-methoxy-1h-indol-3-yl ethyl acetamide, melatol, melatonex, melovine
• PubChem CID: 896
• ChEBI: CHEBI:16796
• IUPAC Name: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
• SMILES: CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC

• Melting Point: 116.0°C to 120.0°C
• Color: Cream to Yellow or White
• Loss on Drying: 0.5% max. (1 g, 105°C)
• Infrared Spectrum: Authentic
• Assay Percent Range: 98.5% min. (HPLC)
• Packaging: Glass bottle
• Quantity: 250 mg
• Beilstein: 22, V,12, 42
• Merck Index: 15, 5884
• Solubility Information: Solubility in water: insoluble. Other solubilities: soluble in ethanol,benzene,toluene,hexane,acet,onitrile
• Formula Weight: 232.28
• Percent Purity: 99%
• Physical Form: Powder
• Chemical Name or Material: Melatonine

RUO – Research Use Only