Methyl chloroacetate, 99+%, Thermo Scientific Chemicals

Description

Methyl chloroacetate is used as a solvent and chemical intermediate. It acts as a precursor in the preparation of (carboxymethyl) trimethylammonium chloride esters. Further, it is used in the preparation of octakis-(carbethoxymethoxy)calix[8]arene. It is employed as an extraction solvent during the separation of neutral compounds. In addition to this, it is used in the synthesis of dimethyl carbonate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methyl chloroacetate is used as a solvent and chemical intermediate. It acts as a precursor in the preparation of (carboxymethyl) trimethylammonium chloride esters. Further, it is used in the preparation of octakis-(carbethoxymethoxy)calix[8]arene. It is employed as an extraction solvent during the separation of neutral compounds. In addition to this, it is used in the synthesis of dimethyl carbonate.

Solubility
Miscible with organic solvents, alcohol, ether, acetone and benzene. Slightly miscible with water.

Notes
Incompatible with strong oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 96-34-4
• Molecular Formula: C3H5ClO2
• Molecular Weight (g/mol): 108.521
• MDL Number: MFCD00000931
• InChI Key: QABLOFMHHSOFRJ-UHFFFAOYSA-N
• Synonym: methyl chloroacetate, chloroacetic acid methyl ester, methyl monochloroacetate, methyl chloroethanoate, acetic acid, chloro-, methyl ester, methyl monochloracetate, methyl alpha-chloroacetate, methylchloroacetate, unii-450vsb182i, ccris 7749
• PubChem CID: 7295
• IUPAC Name: methyl 2-chloroacetate
• SMILES: COC(=O)CCl

• Melting Point: -32°C
• Density: 1.236
• Boiling Point: 128°C to 130°C
• Flash Point: 51°C (123°F)
• Refractive Index: 1.422
• Quantity: 250 g
• UN Number: UN2295
• Beilstein: 506255
• Merck Index: 14,6042
• Solubility Information: Miscible with organic solvents,alcohol,ether,acetone and benzene. Slightly miscible with water.
• Formula Weight: 108.52
• Percent Purity: ≥99%
• Chemical Name or Material: Methyl chloroacetate

Safety and Handling

Product Identifier

• Methyl chloroacetate

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 2
• Acute toxicity Category 3
• ACUTE AQUATIC Acute 1
• Serious eye damage/eye irritation Category 1
• Flammable liquid Category 3
• Skin corrosion/irritation Category 2
• Skin sensitiser Category 1
• Specific target organ toxicity Category 3

Hazard Statement

• H226-Flammable liquid and vapour.
• H301-Toxic if swallowed.
• H310-Fatal in contact with skin.
• H315-Causes skin irritation.
• H317-May cause an allergic skin reaction.
• H318-Causes serious eye damage.
• H330-Fatal if inhaled.
• H335-May cause respiratory irritation.
• H400-Very toxic to aquatic life.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Methyl chloroacetate

RUO – Research Use Only