Methyl piperidine-4-carboxylate, 98%, Thermo Scientific Chemicals

Description

Methyl piperidine-4-carboxylate is a reactant for C-2 arylation of piperidines through directed transition metal-catalyzed sp3 C-H activation. It is used as a reactant for synthesis of antitubercular agents, aminopyrazine inhibitors, orally available naphthyridine protein kinase D inhibitors and a scalable catalyst from asymmetric hydrogenation of sterically demanding aryl enamide.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methyl piperidine-4-carboxylate is a reactant for C-2 arylation of piperidines through directed transition metal-catalyzed sp3 C-H activation. It is used as a reactant for synthesis of antitubercular agents, aminopyrazine inhibitors, orally available naphthyridine protein kinase D inhibitors and a scalable catalyst from asymmetric hydrogenation of sterically demanding aryl enamide.

Solubility
Slightly soluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 2971-79-1
• Molecular Formula: C7H13NO2
• Molecular Weight (g/mol): 143.19
• MDL Number: MFCD00190578
• InChI Key: RZVWBASHHLFBJF-UHFFFAOYSA-N
• Synonym: methyl isonipecotate, methyl 4-piperidinecarboxylate, 4-piperidinecarboxylic acid, methyl ester, piperidine-4-carboxylic acid methyl ester, 4-piperidinecarboxylic acid methyl ester, isonipecotic acid methyl ester, methylpiperidine-4-carboxylate, methylisonipecotate, methyl piperidin-4-carboxylate, acmc-20aiv4
• PubChem CID: 424914
• IUPAC Name: methyl piperidine-4-carboxylate
• SMILES: COC(=O)C1CCNCC1

• Color: Colorless to Yellow
• Density: 1.06 g/mL
• Boiling Point: 85°C to 90°C
• Flash Point: 89°C (192°F)
• Refractive Index: 1.465
• Quantity: 100 g
• Beilstein: 224128
• Solubility Information: Slightly soluble in water.
• Formula Weight: 143.18
• Percent Purity: 98%
• Physical Form: Liquid
• Chemical Name or Material: Methyl piperidine-4-carboxylate

RUO – Research Use Only