Methylprednisolone, Tocris Bioscience™

Description

Glucocorticoid receptor agonist

Glucocorticoid receptor (GR) agonist. Displays anti-inflammatory and antioxidant properties. Attenuates apoptosis in oligodendrocytes after injury stimuli. Upregulates expression of Bcl-xL via direct binding of the GR/STAT5 complex. Neuroprotective.

Specifications

• CAS: 83-43-2
• Molecular Formula: C22H30O5
• MDL Number: MFCD00010591
• Quantity: 50 mg
• Synonym: methylprednisolone, medrol, medrone, urbason, methylprednisolon, 6alpha-methylprednisolone, metilbetasone, medrate, metilprednisolone, dopomedrol
• InChI Key: VHRSUDSXCMQTMA-PJHHCJLFSA-N
• SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
• IUPAC Name: (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
• Molecular Weight (g/mol): 374.48
• PubChem CID: 6741
• ChEBI: CHEBI:6888
• Formula Weight: 374.47
• Percent Purity: >99%
• Chemical Name or Material: Methylprednisolone