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Thermo Scientific Chemicals Metronidazole, 99%

Product Code. 10666792
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Quantity:
5 g
100 g
500 g
Packaging:
Glass bottle
Plastic bottle
This item is not returnable. View return policy
This item is not returnable. View return policy

Metronidazole, CAS# 443-48-1, is a member of the class of imidazoles with limited antibiotic activity that acts against protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities and acts against protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria
• Metronidazole is considered a prodrug that produces nitroso-containing intermediates in the cell that can covalently bind DNA, disrupting helical structure, inducing DNA strand breaks, and inhibiting bacterial nucleic acid synthesis, that results in bacterial cell death

Applications

• Metronidazole shows anti-parasitic and anti-amoebic activities.
• It has been used to prevent the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as Peptostreptococcus and Clostridia. This compound affects a high percentage of gram-negative bacteria and has higher tissue penetration that gives it an advantage compared to other compounds.
• This compound was used initially to suppress protozoans such as Entamoeba histolytica, Giardia lamblia, and Trichomonas vaginalis.
• It has been commonly applied for the eradication of Helicobacter pylori.
• It also has a radio-sensitizing effect on hypoxic tumor cells and can have a mutagenic activity in in vivo animal models.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 443-48-1
Molecular Formula C6H9N3O3
Molecular Weight (g/mol) 171.16
MDL Number MFCD00009750
InChI Key VAOCPAMSLUNLGC-UHFFFAOYSA-N
Synonym metronidazole, metronidazol, flagyl, 2-methyl-5-nitroimidazole-1-ethanol, anagiardil, trichazol, gineflavir, meronidal, metronidaz, novonidazol
PubChem CID 4173
ChEBI CHEBI:6909
IUPAC Name 2-(2-methyl-5-nitroimidazol-1-yl)ethanol
SMILES CC1=NC=C(N1CCO)[N+](=O)[O-]

Specifications

CAS Min % 98.5
CAS Max % 100.0
Melting Point 159°C to 163°C
Color White to Yellow
Infrared Spectrum Authentic
Assay Percent Range 99%
Packaging Plastic bottle
Quantity 100 g
Merck Index 15, 6236
Solubility Information Solubility in water: 1g/100mL (20°C). Other solubilities: soluble in diluted acids,0.5g/100mL ethanol- <0.05g/100mL ether (20°C),<0.05g/100mL chloroform (20°C),sparingly soluble in dmf
Formula Weight 171.16
Percent Purity 99%
Physical Form Crystalline Powder
Chemical Name or Material Metronidazole
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compliance-icons
Product Identifier
  • Metronidazole
Signal Word
  • Warning
Hazard Category
  • Carcinogenicity Category 2
Hazard Statement
  • H351-Suspected of causing cancer.
Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.

RUO – Research Use Only

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