Morpholine, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11424153	Thermo Scientific Alfa Aesar A10355.22	100 g
11434153	Thermo Scientific Alfa Aesar A10355.36	500 g
11444153	Thermo Scientific Alfa Aesar A10355.0E	2500 g

Description

Morpholine is a common additive for pH adjustment in both fossil fuel and nuclear power plant steam systems. It is widely used in organic synthesis as a building block in the preparation of the antibiotic linezolid, the anticancer agent gefitinib and the analgesic dextromoramide. It is also used as a solvent in chemical reactions and in the preparation of enamines. Further, it serves as a chemical emulsifier in the process of waxing fruit.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Morpholine is a common additive for pH adjustment in both fossil fuel and nuclear power plant steam systems. It is widely used in organic synthesis as a building block in the preparation of the antibiotic linezolid, the anticancer agent gefitinib and the analgesic dextromoramide. It is also used as a solvent in chemical reactions and in the preparation of enamines. Further, it serves as a chemical emulsifier in the process of waxing fruit.

Solubility
Miscible with water.      

Notes
Hygroscopic. Incompatible with strong oxidizing agents.

Chemical Identifiers

• CAS: 110-91-8
• Molecular Weight (g/mol): 87.12
• InChI Key: YNAVUWVOSKDBBP-UHFFFAOYSA-N
• PubChem CID: 8083
• IUPAC Name: morpholine

• Molecular Formula: C4H9NO
• MDL Number: MFCD00005972
• Synonym: 1-oxa-4-azacyclohexane, tetrahydro-1,4-oxazine, diethylene oximide, diethylenimide oxide, diethyleneimide oxide, drewamine, diethylene imidoxide, tetrahydro-p-oxazine, tetrahydro-2h-1,4-oxazine, p-isoxazine, tetrahydro
• ChEBI: CHEBI:34856
• SMILES: C1COCCN1

Specifications

• CAS: 110-91-8
• Density: 1.007
• Flash Point: 35°C (95°F)
• Odor: Amine-like
• Refractive Index: 1.454
• UN Number: UN2054
• Sensitivity: Hygroscopic
• Synonym: 1-oxa-4-azacyclohexane, tetrahydro-1,4-oxazine, diethylene oximide, diethylenimide oxide, diethyleneimide oxide, drewamine, diethylene imidoxide, tetrahydro-p-oxazine, tetrahydro-2h-1,4-oxazine, p-isoxazine, tetrahydro
• InChI Key: YNAVUWVOSKDBBP-UHFFFAOYSA-N
• IUPAC Name: morpholine
• PubChem CID: 8083
• Formula Weight: 87.12
• Chemical Name or Material: Morpholine

• Melting Point: -5°C
• Boiling Point: 129°C
• Assay Percent Range: 99%
• Molecular Formula: C4H9NO
• MDL Number: MFCD00005972
• Beilstein: 102549
• Merck Index: 14,6277
• Solubility Information: Miscible with water.
• SMILES: C1COCCN1
• Molecular Weight (g/mol): 87.12
• ChEBI: CHEBI:34856
• Percent Purity: 99%

Safety and Handling

GHS H Statement
H314-H226-H302-H312-H332
Causes severe skin burns and eye damage.
Flammable liquid and vapor.
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.

P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c

H226-H302-H311+H331-H314-H335-H373

missing translation for 'dotInformation' : Transport Hazard Class: 8; Packing Group: I; Proper Shipping Name: MORPHOLINE

missing translation for 'einecsNumber' : 203-815-1

missing translation for 'rtecsNumber' : QD6475000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• Morpholine

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 1
• Flammable liquid Category 3
• Reproductive toxicity Category 2
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H226-Flammable liquid and vapour.
• H302-Harmful if swallowed.
• H311-Toxic in contact with skin.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• H331-Toxic if inhaled.
• H361fd-Suspected of damaging fertility. Suspected of damaging the unborn child.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Morpholine

RUO – Research Use Only