Mouse IgG1 Isotype Control, Invitrogen™

Mouse Isotype Control

Brand:  Invitrogen MA518095

Product Code. 15327374

Description

MA5-18095 is negative on all human cells and cell lines tested. This antibody recognizes a rat cell surface marker, and therefore cannot be used as a negative control in this species. This product is a Low Endotoxin formulation, <0.01 EU/ug. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL.

Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen. It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response. Mouse IgG1 is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity. It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation. Mouse IgG1 is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry. It is also used in therapeutic applications, such as immunotherapy and vaccine development.

Specifications

• Antigen: Mouse IgG1
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Not Applicable
• Form: Liquid

• Applications: Control, Flow Cytometry, Immunohistochemistry (Frozen)
• Conjugate: Unconjugated
• Gene Alias: IgG1; Igh-4; Ighg1; Immunoglobulin G; Immunoglobulin G1; immunoglobulin heavy constant gamma 1 (G1m marker); ImmunoglobulinG; ImmunoglobulinG1; VH7183
• Immunogen: Rat thymocyte membrane glycoproteins
• Quantity: 500 μg
• Primary or Secondary: Isotype Control (Primary)
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Isotype: IgG1