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Gibco™ Mouse SCF Recombinant Protein, PeproTech®

E. coli Recombinant Protein

£64.75 - £1922.00

Specifications

Accession Number P20826
For Use With (Application) ELISA, Functional Assay, Western Blot
Formulation protein with no preservative
Gene ID (Entrez) 17311
Molecular Weight (g/mol) 18.3
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Products 7
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17820863
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Gibco™
250-03-100UG
100 μg
£416.00
100µg
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17829952
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Gibco™
250-03-10UG
10 μg
£157.00
10µg
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17821693
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Gibco™
250-03-1MG
1 mg
£1922.00
1mg
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17820723
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Gibco™
250-03-250UG
250 μg
£674.00
250µg
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17801303
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Gibco™
250-03-2UG
2 μg
£64.75
2µg
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17870513
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Gibco™
250-03-500UG
500 μg
£1156.00
500µg
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17880823
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Gibco™
250-03-50UG
50 μg
£248.00
50µg
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Description

Description

Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.
Specifications

Specifications

P20826
protein with no preservative
18.3
E. coli
RUO
710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Mouse
Recombinant
Lyophilized
ELISA, Functional Assay, Western Blot
17311
Mouse SCF
-20°C
<1 EU/μg
Kitl
Unconjugated
MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA
≥ 98% by SDS-PAGE gel and HPLC analyses.
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