MRS 2179 tetrasodium salt, Tocris Bioscience™

Description

Selective P2Y1 antagonist

A competitive antagonist at P2Y1 receptors (KB = 100 nM). Selective over P2X1 (IC50 = 1.15 μM), P2X3 (IC50 = 12.9 μM), P2X2, P2X4, P2Y2, P2Y4 and P2Y6 receptors. Inhibits the upregulation of NTPDase1 by ATPγS.

Specifications

Chemical Identifiers

• CAS: 1454889-37-2
• Molecular Formula: C11H17N5Na4O9P2
• Molecular Weight (g/mol): 517.19
• InChI Key: HLJPLHFSEAJJGC-ZKRIHRHSSA-N
• Synonym: 2'-Deoxy-N6-methyladenosine 3', 5'-bisphosphate tetrasodium salt
• PubChem CID: 131848299
• IUPAC Name: [(2R,3S,5R)-5-[6-(methylamino)purin-9-yl]-2-(phosphonooxymethyl)oxolan-3-yl] dihydrogen phosphate;sodium
• SMILES: CNC1=NC=NC2=C1N=CN2C3CC(C(O3)COP(=O)(O)O)OP(=O)(O)O.[Na].[Na].[Na].[Na]

• Quantity: 10 mg
• Formula Weight: 513.16
• Percent Purity: >98%
• Chemical Name or Material: MRS 2179 tetrasodium salt