N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11484514	Thermo Scientific Alfa Aesar A13143.03	1 g
11494514	Thermo Scientific Alfa Aesar A13143.06	5 g
11404524	Thermo Scientific Alfa Aesar A13143.14	25 g

Description

N-(9-Fluorenylmethoxycarbonyloxy)succinimide is the most efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxy-amino acids. Dipeptide formation is lower than with the chloroformate, Fmoc-Cl. It is also employed in the synthesis of glycopeptides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-(9-Fluorenylmethoxycarbonyloxy)succinimide is the most efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxy-amino acids. Dipeptide formation is lower than with the chloroformate, Fmoc-Cl. It is also employed in the synthesis of glycopeptides.

Solubility
Soluble in dimethyl sulfoxide and dimethyl formamide.

Notes
Store in a cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids.

Chemical Identifiers

• CAS: 82911-69-1
• Molecular Weight (g/mol): 337.331
• InChI Key: WMSUFWLPZLCIHP-UHFFFAOYSA-N
• PubChem CID: 134122
• SMILES: C1CC(=O)N(C1=O)OC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

• Molecular Formula: C19H15NO5
• MDL Number: MFCD00010733
• Synonym: fmoc-osu, n-9-fluorenylmethoxycarbonyloxy succinimide, fmoc-onsu, 9-fluorenylmethyl succinimidyl carbonate, fmoc n-hydroxysuccinimide ester, 9h-fluoren-9-yl methyl 2,5-dioxopyrrolidin-1-yl carbonate, 9-fluorenylmethyl n-succinimidyl carbonate, 9-fluorenylmethylsuccinimidyl carbonate, 9-fluorenylmethoxycarbonyl-n-hydroxysuccinimide
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate

Specifications

• CAS: 82911-69-1
• Molecular Formula: C19H15NO5
• UN Number: UN3077
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in dimethyl sulfoxide and dimethyl formamide.
• SMILES: C1CC(=O)N(C1=O)OC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
• Molecular Weight (g/mol): 337.331
• Formula Weight: 337.34
• Chemical Name or Material: N-(9-Fluorenylmethoxycarbonyloxy)succinimide

• Melting Point: 150°C to 153°C
• MDL Number: MFCD00010733
• Beilstein: 3569540
• Synonym: fmoc-osu, n-9-fluorenylmethoxycarbonyloxy succinimide, fmoc-onsu, 9-fluorenylmethyl succinimidyl carbonate, fmoc n-hydroxysuccinimide ester, 9h-fluoren-9-yl methyl 2,5-dioxopyrrolidin-1-yl carbonate, 9-fluorenylmethyl n-succinimidyl carbonate, 9-fluorenylmethylsuccinimidyl carbonate, 9-fluorenylmethoxycarbonyl-n-hydroxysuccinimide
• InChI Key: WMSUFWLPZLCIHP-UHFFFAOYSA-N
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate
• PubChem CID: 134122
• Percent Purity: 98%

Safety and Handling

GHS H Statement
H301-H317
Toxic if swallowed.
May cause an allergic skin reaction.

P261-P264b-P270-P272-P280g-P301+P312-P302+P352-P330-P333+P313-P363-P501c

H302-H317

missing translation for 'dotInformation' : Transport Hazard Class: 9; Packing Group: III; Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCES, SOLID, N.O.S.

missing translation for 'einecsNumber' : 433-520-5

missing translation for 'tsca' : No

Recommended Storage : Keep cold

RUO – Research Use Only