N,N-Dimethylformamide dimethyl acetal, 97%, Thermo Scientific Chemicals

Description

N,N-Dimethylformamide dimethyl acetal is used as an intermediate in the formation of pyridine derivatives, which exhibits inhibition against PI3 kinase p110alfa enzymes. It is utilized for the derivatization of primary sulfonamides and trifluoroacetic acid. It is also used in the preparation of formamidine derivatives. It is used as a reagent for n-dimethylaminomethylene and methyl esters. Further, it is used to catalyze the coupling of epoxides with carbon dioxide to prepare cyclic carbonates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N-Dimethylformamide dimethyl acetal is used as an intermediate in the formation of pyridine derivatives, which exhibits inhibition against PI3 kinase p110alfa enzymes. It is utilized for the derivatization of primary sulfonamides and trifluoroacetic acid. It is also used in the preparation of formamidine derivatives. It is used as a reagent for n-dimethylaminomethylene and methyl esters. Further, it is used to catalyze the coupling of epoxides with carbon dioxide to prepare cyclic carbonates.

Solubility
Miscible with most organic solvents.

Notes
Moisture sensitive. Incompatible with strong oxidizing agents and acids.

Specifications

Chemical Identifiers

• CAS: 4637-24-5
• Molecular Formula: C5H13NO2
• Molecular Weight (g/mol): 119.16
• MDL Number: MFCD00008482
• InChI Key: ZSXGLVDWWRXATF-UHFFFAOYSA-N
• Synonym: n,n-dimethylformamide dimethyl acetal, 1,1-dimethoxytrimethylamine, dimethoxymethyl dimethylamine, methanamine, 1,1-dimethoxy-n,n-dimethyl, dimethylformamide-dimethylacetal, dmf dimethyl acetal, dmfdma, dimethylformamide dimethyl acetal, 1,1-dimethoxy-n,n-dimethylmethylamine, dimethoxy dimethylamino methane
• PubChem CID: 78373
• ChEBI: CHEBI:85061
• IUPAC Name: (dimethoxymethyl)dimethylamine
• SMILES: COC(OC)N(C)C

• Melting Point: -85°C
• Density: 0.897
• Boiling Point: 102°C to 104°C
• Flash Point: 7°C (45°F)
• Refractive Index: 1.3972
• Quantity: 100 g
• UN Number: UN1993
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with most organic solvents.
• Formula Weight: 119.16
• Percent Purity: 97%
• Chemical Name or Material: N,N-Dimethylformamide dimethyl acetal

Safety and Handling

Product Identifier

• N,N-Dimethylformamide dimethyl acetal

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 1
• Flammable liquid Category 2
• Skin sensitiser Category 1

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H317-May cause an allergic skin reaction.
• H318-Causes serious eye damage.
• H332-Harmful if inhaled.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : N,N-Dimethylformamide dimethyl acetal

RUO – Research Use Only