N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, Thermo Scientific Chemicals

Description

N,O-Bis(trimethylsilyl)trifluoroacetamide is used as a derivatization reagent for gas chromatography and mass-spectrometry analysis of phenolic acids in fruits. It is also used as a reactant in the preparation of pyrimidinone ribosides and analogs which shows anti-tumor properties. It plays as an important role as a reagent for the regioselective desulfation of polysaccharide sulfates. Furthermore, it is used to prepare trimethylsilyl ethers of carbohydrates and alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Ampouled under argon

Specifications

Chemical Identifiers

• CAS: 25561-30-2
• Molecular Formula: C8H18F3NOSi2
• Molecular Weight (g/mol): 257.403
• MDL Number: MFCD00008269
• InChI Key: XCOBLONWWXQEBS-GHXNOFRVSA-N
• Synonym: bstfa, n,o-bis trimethylsilyl trifluoroacetamide, acetamide, 2,2,2-trifluoro-o,n-bis trimethylsilyl, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl acetimidate, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanimidate, trimethylsilyl 1z-2,2,2-trifluoro-n-z-trimethylsilyl ethanimidoate #, n,o-bis trimethylsilyl trifluoroacetamide bstfa, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanecarboximidate
• PubChem CID: 9601896
• IUPAC Name: trimethylsilyl (1Z)-2,2,2-trifluoro-N-trimethylsilylethanimidate
• SMILES: C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C

• Melting Point: -10°C
• Color: Colorless to Yellow
• Density: 0.97 g/mL
• Boiling Point: 145°C to 147°C
• Flash Point: 23°C (73°F)
• Packaging: Ampule
• Refractive Index: 1.384
• Quantity: 5 x 1 g
• UN Number: UN2924
• Beilstein: 3607620
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with chloroform.
• Formula Weight: 257.4
• Physical Form: Liquid
• Chemical Name or Material: N,O-Bis (trimethylsilyl)trifluoroacetamide, With 1% TMCS

Safety and Handling

Product Identifier

• N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Flammable liquid Category 3
• Skin corrosion/irritation Category 2

Hazard Statement

• H226-Flammable liquid and vapour.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• EUH014-Reacts violently with water.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate

RUO – Research Use Only