n-Octyl-beta-D-thioglucopyranoside, 98+%, Thermo Scientific Chemicals

Description

Non-ionic detergent used for the solubilization of membrane proteins

n-Octyl-beta-D-thioglucopyranoside is used for cell lysis or to solubilise membrane proteins without denaturing them. This is particularly of use in order to crystallise them or to reconstitute them into lipid bilayers. It has been used in a study to assess the crystallization and preliminary x-ray analysis of human plasma apolipoprotein C-I. It has also been used in a study that investigated the identification of Chlamydia pneumoniae proteins.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
n-Octyl-beta-D-thioglucopyranoside is used for cell lysis or to solubilise membrane proteins without denaturing them. This is particularly of use in order to crystallise them or to reconstitute them into lipid bilayers. It has been used in a study to assess the crystallization and preliminary x-ray analysis of human plasma apolipoprotein C-I. It has also been used in a study that investigated the identification of Chlamydia pneumoniae proteins.

Solubility
Soluble in ethanol, water or methanol

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 85618-21-9
• Molecular Formula: C14H28O5S
• Molecular Weight (g/mol): 308.433
• MDL Number: MFCD00012189
• InChI Key: CGVLVOOFCGWBCS-DGTMBMJNSA-N
• Synonym: octyl thioglucopyranoside, octyl-i 2-d-1-thioglucopyranoside
• PubChem CID: 53720324
• IUPAC Name: (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-octylsulfanyloxane-3,4,5-triol
• SMILES: CCCCCCCCSC1C(C(C(C(O1)CO)O)O)O

• Melting Point: 128°C
• Color: White
• Quantity: 2.5 g
• Beilstein: 4182783
• Solubility Information: Soluble in ethanol, water or methanol
• Formula Weight: 308.44
• Percent Purity: ≥98%
• Physical Form: Crystalline Powder
• Chemical Name or Material: n-Octyl-beta-D-thioglucopyranoside

RUO – Research Use Only