NAADP tetrasodium salt, Tocris Bioscience™

Description

Ca2+ mobilizing agent

Ca2+ mobilizing agent. Initiates Ca2+ release via type 1 ryanodine receptor (RyR1) activation. Also regulates Ca2+ release from intracellular stores distinct from the endoplasmic reticulum (ER); displays affinity for two-pore channels (TPCs) which release Ca2+ from acidic organelles.

Specifications

• CAS: 5502-96-5
• Molecular Formula: C21H23N6Na4O18P3
• Quantity: 10 mg
• Synonym: naadp, naadp tetrasodium salt
• InChI Key: NWKIGVGTZIAOCW-MCNGMCCKSA-J
• SMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C4N=CN=C5N)OP(=O)([O-])[O-])O)O)O)C(=O)[O-].[Na+].[Na+].[Na+].[Na+]
• IUPAC Name: tetrasodium;1-[(2R,3R,4S,5R)-5-[[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonatooxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]pyridin-1-ium-3-carboxylate
• Molecular Weight (g/mol): 832.319
• PubChem CID: 90488897
• Formula Weight: 832.32
• Percent Purity: >98%
• Chemical Name or Material: NAADP tetrasodium salt