Nicotinamide, Tocris Bioscience™

Description

PARP-1 inhibitor

Nicotinamide is an anti-inflammatory agent. Inhibitor of poly(ADP-ribose) polymerase (PARP-1) enzymes. NAD+ precursor. Promotes differentiation of mesenchymal stem cells to insulin producing cells when used in combination with growth factors and high glucose concentration. Nicotinamide also acts as a SIRT1 inhibitor and promotes the expansion of hematopoietic progenitor cells

For more information about how Nicotinamide may be used, see our protocol:

3D Culture of Lung Alveolar Cells

Specifications

• CAS: 98-92-0
• Molecular Formula: C6H6N2O
• Quantity: 50 mg
• Synonym: nicotinamide, niacinamide, 3-pyridinecarboxamide, vitamin pp, nicotinic acid amide, papulex, aminicotin, amixicotyn, nicobion, nicotylamide
• InChI Key: DFPAKSUCGFBDDF-UHFFFAOYSA-N
• SMILES: C1=CC(=CN=C1)C(=O)N
• IUPAC Name: pyridine-3-carboxamide
• Molecular Weight (g/mol): 122.127
• PubChem CID: 936
• ChEBI: CHEBI:17154
• Formula Weight: 122.12
• Percent Purity: >99%
• Chemical Name or Material: Nicotinamide