Nitrilotriacetic acid, trisodium salt, monohydrate, 99+%, Thermo Scientific Chemicals

Description

Nitrilotriacetic acid, trisodium salt, monohydrate, CAS # 18662-53-8, is considered a non-genotoxic compound showing carcinogenic activity and is used as an inducer of tumorigenesis in laboratory studies using animal models.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Nitrilotriacetic acid, trisodium salt, monohydrate is considered to be a nongenotoxic compound with carcinogenic activity
• This compound inhibits gap-junctional communication between Chinese hamster lung fibroblasts

Applications

• Nitrilotriacetic acid trisodium salt monohydrate is commonly used in laboratory experiments due to its capacity to induce the tumorigenic process
• It has been used in in vivo experiments as an inducer of bladder and kidney tumors in animal models
• It is used as a chelating agent, which forms coordination compounds with metal ions (chelates)

Literature References
Malcolm, A.; Mills, L. Inhibition of gap-junctional intercellular communication between Chinese hamster lung fibroblasts by di(2-ethylhexyl) phthalate (DEHP) and trisodium nitrilotriacetate monohydrate (NTA). Cell Biology and Toxicology. 1989, 5, 145–153.

Specifications

Chemical Identifiers

• CAS: 18662-53-8
• Molecular Formula: C₆H₆NNa₃O₆·H₂O
• Molecular Weight (g/mol): 275.09
• InChI Key: HERBOKBJKVUALN-UHFFFAOYSA-K
• Synonym: trisodium nitrilotriacetate monohydrate, nitrilotriacetic acid trisodium salt monohydrate, nta sodium hydrate, nta trisodium salt dihydrate, unii-j0u92u6nu5, ccris 437, nitrilotriacetic acid trisodium salt, monohydrate, nitriloacetic acid trisodium salt monohydrate, glycine, n,n-bis carboxymethyl-, trisodium salt, monohydrate, nitrilotriacetic acid, trisodium salt monohydrate
• PubChem CID: 29194
• IUPAC Name: trisodium;2-[bis(carboxylatomethyl)amino]acetate;hydrate
• SMILES: C(C(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].O.[Na+].[Na+].[Na+]

• Melting Point: >320.0°C
• Color: White
• Infrared Spectrum: Authentic
• Assay Percent Range: 99+%
• Packaging: Plastic bottle
• Linear Formula: N(CH₂CO₂Na)₃·H₂O
• Quantity: 25 g
• Solubility Information: Solubility in water: 484g/L (25°C)
• Formula Weight: 275.09
• Percent Purity: 99+%
• Physical Form: Powder, Crystals or Chunks
• Chemical Name or Material: Nitrilotriacetic acid, trisodium salt, monohydrate

RUO – Research Use Only