NS 1619, Tocris Bioscience™

Description

Activator of BKCa (KCa1.1) channels

Large-conductance Ca2+-activated potassium (BKCa, KCa1.1) channel activator. Induces a concentration-dependent decrease in mitochondrial membrane potential (EC50 = 3.6 μM).

Specifications

• CAS: 153587-01-0
• Molecular Formula: C15H8F6N2O2
• Quantity: 10 mg
• Synonym: 1-2-hydroxy-5-trifluoromethyl phenyl-5-trifluoromethyl-1h-benzo d imidazol-2 3h-one, 1,3-dihydro-1-2-hydroxy-5-trifluoromethyl phenyl-5-trifluoromethyl-2h-benzimidazol-2-one, 1-2'-hydroxy-5'-trifluoromethylphenyl-5-trifluoromethyl-2 3h-benzimidazolone, 1-2-hydroxy-5-trifluoromethyl phenyl-5-trifluoromethyl-1,3-dihydro-2h-benzimidazol-2-one, 3-2-hydroxy-5-trifluoromethyl phenyl-6-trifluoromethyl-1h-benzimidazol-2-one, 2h-benzimidazol-2-one,1,3-dihydro-1-2-hydroxy-5-trifluoromethyl phenyl-5-trifluoromethyl, 1-2-hydroxy-5-trifluoromethyl phenyl-5-trifluoromethyl-3h-1,3-benzodiazol-2-one, acmc-20agb2, ns 1619, powder, lopac-n-170
• InChI Key: YLFMCMWKHSDUCT-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C=C1C(F)(F)F)NC(=O)N2C3=C(C=CC(=C3)C(F)(F)F)O
• IUPAC Name: 3-[2-hydroxy-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-1H-benzimidazol-2-one
• Molecular Weight (g/mol): 362.231
• PubChem CID: 4552
• ChEBI: CHEBI:34879
• Formula Weight: 362.23
• Percent Purity: >98%
• Chemical Name or Material: NS 1619