NU 9056, Tocris Bioscience™

Beschreibung

Inhibitor of KAT5 (Tip60)

Selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively). Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.

Spezifikation

• CAS: 1450644-28-6
• Molecular Formula: C6H4N2S4
• Quantity: 10 mg
• Synonym: 5-1,2-thiazol-5-yldisulfanyl-1,2-thiazole, 1,2-bis isothiazol-5-yl disulfane
• InChI Key: MLRAMCAHIWHWRM-UHFFFAOYSA-N
• Molecular Weight (g/mol): 232.35
• PubChem CID: 72201043
• Formula Weight: 232.37
• Percent Purity: >98%
• Chemical Name or Material: NU 9056