Tocris Bioscience™ NVP ADW 742

ATP-competitive inhibitor of IGF1R

Brand:  Tocris Bioscience™ 5247/10

Product Code. 18753968

Description

NVP ADW 742 is an ATP-competitive inhibitor of IGF1R (IC50 in the range of 0.1-0.2 μM). Also inhibits c-Kit kinase activity (IC50 in the range of 3-5 μM). Exhibits a synergistic effect with Imatinib (Cat. No. 5906), enhancing the sensitivity of multiple small cell lung cancer cell lines to the chemotherapeutics Etoposide (Cat. No. 1226) and Carboplatin (Cat. No. 2626).

Specifications

• Purity: >99%
• Product Type: NVP ADW 742
• Inhibitors: NVP ADW 742

• Quantity: 10 mg
• Molecular Weight (g/mol): 453.58

For Research Use Only