O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11382029	Thermo Scientific Alfa Aesar H26082.03	1 g
11392029	Thermo Scientific Alfa Aesar H26082.06	5 g
11302039	Thermo Scientific Alfa Aesar H26082.14	25 g

Description

O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is a coupling reagent and used as an additive in peptide synthesis., It is also involved efficiently to speed up the coupling process and reduces the loss of chiral integrity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate is a coupling reagent and used as an additive in peptide synthesis., It is also involved efficiently to speed up the coupling process and reduces the loss of chiral integrity.

Solubility
Soluble in acetonitrile. Insoluble in water.

Notes
Moisture sensitive. Incompatible with oxidizing agents and highly acidic or alkaline materials.

Chemical Identifiers

• CAS: 148893-10-1
• Molecular Weight (g/mol): 380.24
• InChI Key: JNWBBCNCSMBKNE-UHFFFAOYSA-N
• PubChem CID: 9886157
• SMILES: F[P-](F)(F)(F)(F)F.CN(C)C(ON1N=NC2=CC=CN=C12)=[N+](C)C

• Molecular Formula: C10H15F6N6OP
• MDL Number: MFCD00274639
• Synonym: hatu, 2-7-aza-1h-benzotriazole-1-yl-1,1,3,3-tetramethyluronium hexafluorophosphate, o-7-azabenzotriazol-1-yl-n,n,n',n'-tetramethyluronium hexafluorophosphate, o-7-azabenzotriazol-1-yl-n,n,n,n-tetramethyl uronium hexafluorophosphate, 2-3h-1,2,3 triazolo 4,5-b pyridin-3-yl-1,1,3,3-tetramethyluronium hexafluorophosphate v, dimethylamino triazolo 4,5-b pyridin-3-yloxy methylene-dimethyl-ammonium hexafluorophosphate, 2-7-aza-1h-benzotriazole-1-yl-1,1,3,3-tetramethyl uronium hexafluorophosphate, 2-3h-1,2,3 triazolo 4,5-b pyridin-3-yl-1,1,3,3-tetramethylisouronium hexafluorophosphate v, n-dimethylamino 3h-1,2,3 triazolo 4,5-b pyridin-3-yloxy methylene-n-methylmethanaminium hexafluorophosphate, n-dimethylamino-1h-1,2,3-triazolo-4,5-b pyridin-1-ylmethylene-n-methylmethanaminium hexafluorophosphate n-oxide
• IUPAC Name: [dimethylamino(triazolo[4,5-b]pyridin-3-yloxy)methylidene]-dimethylazanium;hexafluorophosphate

Specifications

• CAS: 148893-10-1
• Molecular Formula: C10H15F6N6OP
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in acetonitrile. Insoluble in water.
• SMILES: F[P-](F)(F)(F)(F)F.CN(C)C(ON1N=NC2=CC=CN=C12)=[N+](C)C
• Molecular Weight (g/mol): 380.24
• Formula Weight: 380.23
• Chemical Name or Material: O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

• Melting Point: ∼185°C (decomposition)
• MDL Number: MFCD00274639
• Synonym: hatu, 2-7-aza-1h-benzotriazole-1-yl-1,1,3,3-tetramethyluronium hexafluorophosphate, o-7-azabenzotriazol-1-yl-n,n,n',n'-tetramethyluronium hexafluorophosphate, o-7-azabenzotriazol-1-yl-n,n,n,n-tetramethyl uronium hexafluorophosphate, 2-3h-1,2,3 triazolo 4,5-b pyridin-3-yl-1,1,3,3-tetramethyluronium hexafluorophosphate v, dimethylamino triazolo 4,5-b pyridin-3-yloxy methylene-dimethyl-ammonium hexafluorophosphate, 2-7-aza-1h-benzotriazole-1-yl-1,1,3,3-tetramethyl uronium hexafluorophosphate, 2-3h-1,2,3 triazolo 4,5-b pyridin-3-yl-1,1,3,3-tetramethylisouronium hexafluorophosphate v, n-dimethylamino 3h-1,2,3 triazolo 4,5-b pyridin-3-yloxy methylene-n-methylmethanaminium hexafluorophosphate, n-dimethylamino-1h-1,2,3-triazolo-4,5-b pyridin-1-ylmethylene-n-methylmethanaminium hexafluorophosphate n-oxide
• InChI Key: JNWBBCNCSMBKNE-UHFFFAOYSA-N
• IUPAC Name: [dimethylamino(triazolo[4,5-b]pyridin-3-yloxy)methylidene]-dimethylazanium;hexafluorophosphate
• PubChem CID: 9886157
• Percent Purity: 99%

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P210-P240-P241-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c

H228-H315-H319-H335

missing translation for 'dotInformation' : Hazard Class: 4.1; Packaging Group: II

missing translation for 'rtecsNumber' : XZ5633000

missing translation for 'tsca' : No

Recommended Storage : Ambient temperatures; Store under Nitrogen

RUO – Research Use Only