Thermo Scientific Chemicals Ofloxacin, 98%

Description

Ofloxacin, CAS # 82419-36-1, is a fluoroquinolone antibiotic with broad antibacterial activity against gram-positive and -negative bacteria, as well as against mycobacteria.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Ofloxacin is a synthetic fluoroquinolone antibiotic that is an analog of nalidixic acid

Ofloxacin can directly interact with pneumococcal autolysin (LytA) at its choline binding domain, thus inhibiting the ability of LytA to degrade the pneumococcal cell wall

Ofloxacin is racemic and its (S)-enantiomer is levofloxacin

Applications

Ofloxacin may be used in pharmacokinetic laboratory studies and high-throughput drug screens

The DNA and protein-binding capabilities of ofloxacin have been studied in the laboratory

Specifications

Chemical Identifiers

• CAS: 82419-36-1
• Molecular Formula: C18H20FN3O4
• Molecular Weight (g/mol): 361.373
• InChI Key: GSDSWSVVBLHKDQ-UHFFFAOYSA-N
• PubChem CID: 4583
• ChEBI: CHEBI:7731
• SMILES: CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

• Type: Ofloxacin
• Melting Point: 280.0°C to 275.0°C
• Infrared Spectrum: Authentic
• Loss on Drying: 0.2% max.
• Quantity: 5 g
• Solubility Information: Solubility in water: slightly soluble.
• Formula Weight: 361.37
• Percent Purity: 98%
• Chemical Name or Material: Ofloxacin

Safety and Handling

Product Identifier

• Ofloxacin

RUO – Research Use Only