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Olanzapine, Tocris Bioscience™

Product Code. 18752744
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

5-HT2A/D2 antagonist; atypical antipsychotic

Antagonist of 5-HT2A and dopamine D2 receptors (Ki values are 4 and 11 nM respectively). Also displays affinity for a range of other receptors including D1 and D4, 5-HT2C, α1, H1 and M1-4 receptors (Ki values range between 1.9 and 31 nM) . Atypical antipsychotic. Displays anticholinergic properties. Also a highly potent activator of hM4Di DREADDs (EC50 values are 5 nM in vitro and 7 nM in vivo).

Chemical Identifiers

CAS 132539-06-1
Molecular Formula C17H20N4S
Molecular Weight (g/mol) 312.44
MDL Number MFCD00866702
InChI Key WXPNDRBBWZMPQG-UHFFFAOYSA-N
Synonym olanzapine, zyprexa, zyprexa zydis, olansek, zalasta, symbyax, zyprexa intramuscular, zyprexa velotab, 2-methyl-4-4-methylpiperazin-1-yl-10h-benzo b thieno 2,3-e 1,4 diazepine, olanzapina
PubChem CID 4585
IUPAC Name 5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.0³,⁷]tetradeca-1(14),2,5,7,10,12-hexaene
SMILES CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1

Specifications

Quantity 10 mg
Formula Weight 312.43
Percent Purity >99%
Chemical Name or Material Olanzapine
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