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P2X1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA124622

Code : LD

Additional Details : Weight : 0.01000kg

Product Code. 10753575

  • £462.00 / 50µL
Estimated Shipment: 19-08-2024
to see stock.

Description

Description

PA1-24622 is expected to cross react with human (100% conserved) and mouse (100% conserved) due to sequence homology.

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Specifications

Specifications

P2X1
Polyclonal
Unconjugated
P2RX1
AI323649; ATP receptor; BB122383; P2RX1; P2x; P2X purinoceptor 1; P2X receptor, subunit 1; P2X1; P2X1 receptor; P2XMR; Pdcd3; programmed cell death 3; Purinergic receptor; purinergic receptor P2X 1; purinergic receptor P2X, ligand gated ion channel, 1; purinergic receptor P2X, ligand-gated ion channel, 1; purinergic receptor P2X1; purinergic receptor P2X1-1; purinergic receptor P2X1-2; RP-2; RP-2 protein
Rabbit
50 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Immunocytochemistry, Immunohistochemistry (Frozen)
Conc. Not Determined
whole serum with 0.05% sodium azide
P47824, P51575, P51576
P2RX1
Synthetic peptide corresponding to residues G(364) L Q E N M R T S(372) of rat P2X1.
RUO
18436, 25505, 5023
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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