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PDCD2 Monoclonal Antibody (DHIC2-5H10), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA516135
This item is not returnable.
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Description
Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.Specifications
PDCD2 | |
Monoclonal | |
Conc. Not Determined | |
tissue culture supernatant with 0.05% sodium azide | |
Q16342 | |
Pdcd2 | |
Human pancreatic enriched duct cells | |
RUO | |
5134 | |
4° C, do not freeze | |
Liquid |
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen) | |
DHIC2-5H10 | |
Unconjugated | |
Pdcd2 | |
AI528543; hypothetical protein MGC63685; Pcd2; PDCD2; programmed cell death 2; programmed cell death protein 2; RP8; RP-8; zgc:63685; zinc finger MYND domain-containing protein 7; Zinc finger protein Rp-8; ZMYND7 | |
Mouse | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgM |