Penicillin G potassium salt, Thermo Scientific Chemicals

Description

Inhibits bacterial cell wall synthesis

Penicillin G potassium salt is used as a cell culture additive as an antibiotics. Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Penicillin G potassium salt is used as a cell culture additive as an antibiotics. Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

Solubility
Soluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Specifications

Chemical Identifiers

• CAS: 113-98-4
• Molecular Formula: C33H36ClKN4O4S2
• Molecular Weight (g/mol): 691.34
• MDL Number: MFCD00036193
• InChI Key: HTQQVOYPSGNVPA-HBRCYENSSA-M
• Synonym: Benzylpenicillin potassium salt; Potassium benzylpenicillinate
• PubChem CID: 23664709
• ChEBI: CHEBI:7963
• IUPAC Name: potassium [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• SMILES: [K+].CN(C)CCCN1C2=CC=CC=C2SC2=CC=C(Cl)C=C12.CC1(C)S[C@@H]2[C@H](NC(=O)CC3=CC=CC=C3)C(=O)N2[C@H]1C([O-])=O

• Type: Penicillin G Potassium Salt
• Physical Form: Powder
• Color: White
• Quantity: 100 g
• Beilstein: 3832841
• Merck Index: 14,7094
• Solubility Information: Soluble in water (100mg/ml),methanol,ethanol (sparingly),and alcohol. Insoluble in chloroform.
• Formula Weight: 372.48
• Chemical Name or Material: Penicillin G potassium salt

Safety and Handling

Product Identifier

• Penicillin G potassium salt

Signal Word

• Danger

Hazard Category

• Respiratory sensitiser Category 1
• Skin sensitiser Category 1

Hazard Statement

• H317-May cause an allergic skin reaction.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P284-¢In case of inadequate ventilation! wear respiratory protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
• P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .

Supplemental information

• MIXTURE LIST-Contains : 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

RUO – Research Use Only