Penicillin G sodium salt, Thermo Scientific Chemicals

Description

Penicillin G sodium salt, CAS # 69-57-8, also called benzylpenicillin, is a β-lactam antibiotic active against gram-positive and gram-negative bacteria.

Penicillin G sodium salt is used as a β-lactam antibiotic. Penicillin G can be used as a selective agent in several types of isolation media. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Penicillin G sodium salt is the sodium salt of benzylpenicillin, a broad-spectrum β-lactam antibiotic with gram-positive and gram-negative bactericidal activity

• Penicillin G binds and inactivates penicillin-binding-proteins associated with the bacterial cell wall, thus inhibiting cell wall synthesis and resulting in cell lysis

Applications

• Penicillin G can be used as a selection agent in the isolation of microorganisms or in cell culture applications

• It can also be used to prevent infection in research animals

Specifications

Chemical Identifiers

• CAS: 69-57-8
• Molecular Formula: C16H17N2NaO4S
• Molecular Weight (g/mol): 356.372
• MDL Number: MFCD00069666
• InChI Key: FCPVYOBCFFNJFS-LQDWTQKMSA-M
• Synonym: Benzylpenicillin sodium salt
• PubChem CID: 23668834
• ChEBI: CHEBI:51765
• IUPAC Name: sodium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[Na+]

• Type: Penicillin G Sodium Salt
• Physical Form: Powder
• Beilstein: 3834217
• Merck Index: 14,7094
• Solubility Information: Soluble in water (100mg/ml),alcohol,glycerol,DMSO (71mg/ml at 25°C),and ethanol (< 1mg/ml at 25°C).
• Formula Weight: 356.37
• Color: White
• Quantity: 25 g
• Chemical Name or Material: Penicillin G sodium salt

Safety and Handling

Product Identifier

• Penicillin G sodium salt

Signal Word

• Danger

Hazard Category

• Respiratory sensitiser Category 1
• Skin sensitiser Category 1

Hazard Statement

• H317-May cause an allergic skin reaction.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .

RUO – Research Use Only