Phenylacetyl chloride, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11484030	Thermo Scientific Alfa Aesar B24987.22	100 g
11494030	Thermo Scientific Alfa Aesar B24987.36	500 g
11431567	Thermo Scientific Alfa Aesar B24987.0B	1000 g

Description

Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in the preparation of penicillin. Further, it is used to prepare esters for flavorings.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in the preparation of penicillin. Further, it is used to prepare esters for flavorings.

Solubility
Miscible with alcohol and ether.

Notes
Moisture sensitive. Store in a cool place.Incompatible with amines, most common metals, strong bases and strong oxidizing agents.

Chemical Identifiers

• CAS: 103-80-0
• Molecular Weight (g/mol): 154.59
• InChI Key: VMZCDNSFRSVYKQ-UHFFFAOYSA-N
• PubChem CID: 7679
• SMILES: ClC(=O)CC1=CC=CC=C1

• Molecular Formula: C8H7ClO
• MDL Number: MFCD00000729
• Synonym: phenylacetyl chloride, benzeneacetyl chloride, acetyl chloride, phenyl, phenylacetic acid chloride, phenacetyl chloride, phenylacetylchloride, unii-t30899drnd, phenyl acetyl chloride, a-toluoyl chloride, phenylacetyl
• IUPAC Name: 2-phenylacetyl chloride

Specifications

• CAS: 103-80-0
• Boiling Point: 225°C
• Molecular Formula: C8H7ClO
• MDL Number: MFCD00000729
• Beilstein: 742254
• Synonym: phenylacetyl chloride, benzeneacetyl chloride, acetyl chloride, phenyl, phenylacetic acid chloride, phenacetyl chloride, phenylacetylchloride, unii-t30899drnd, phenyl acetyl chloride, a-toluoyl chloride, phenylacetyl
• InChI Key: VMZCDNSFRSVYKQ-UHFFFAOYSA-N
• IUPAC Name: 2-phenylacetyl chloride
• PubChem CID: 7679
• Percent Purity: 98%

• Density: 1.168
• Flash Point: 102°C (215°F)
• Refractive Index: 1.5325
• UN Number: UN2577
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with alcohol and ether.
• SMILES: ClC(=O)CC1=CC=CC=C1
• Molecular Weight (g/mol): 154.59
• Formula Weight: 154.6
• Chemical Name or Material: Phenylacetyl chloride

Safety and Handling

GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.

P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

H314-H500

missing translation for 'dotInformation' : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: PHENYLACETYL CHLORIDE

missing translation for 'einecsNumber' : 203-146-5

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only