Phorbol 12-myristate 13-acetate, 97%, Thermo Scientific Chemicals

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 16561-29-8
• Molecular Formula: C36H56O8
• Molecular Weight (g/mol): 616.84
• MDL Number: MFCD00036736
• InChI Key: PHEDXBVPIONUQT-RGYGYFBISA-N
• Synonym: phorbol 12-myristate 13-acetate, phorbol ester, 12-o-tetradecanoylphorbol-13-acetate, 12-o-tetradecanoylphorbol 13-acetate, factor a1, tetradecanoylphorbol acetate, 12-tetradecanoylphorbol 13-acetate, factor a1 croton oil, phorbol 13-acetate 12-myristate, phorbol-12-myristate-13-acetate
• PubChem CID: 27924
• ChEBI: CHEBI:37537
• IUPAC Name: (1S,2S,6R,10S,11R,13S,14R,15R)-13-(acetyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0²,⁶.0¹¹,¹³]pentadeca-3,8-dien-14-yl tetradecanoate
• SMILES: CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(C)=O

• Melting Point: 72.0°C
• Color: White to Yellow
• Assay Percent Range: 96% min. (HPLC)
• Packaging: Glass bottle
• Quantity: 1 mg
• Merck Index: 14,7332
• Formula Weight: 616.84
• Percent Purity: 97%
• Physical Form: Fine Crystalline Powder
• Chemical Name or Material: Phorbol 12-myristate 13-acetate

Safety and Handling

Product Identifier

• Phorbol 12-myristate 13-acetate

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 1
• Acute toxicity Category 2
• Carcinogenicity Category 2
• Serious eye damage/eye irritation Category 1
• Respiratory sensitiser Category 1
• Skin corrosion/irritation Category 1 B
• Skin sensitiser Category 1

Hazard Statement

• H300-Fatal if swallowed.
• H310-Fatal in contact with skin.
• H314-Causes severe skin burns and eye damage.
• H317-May cause an allergic skin reaction.
• H318-Causes serious eye damage.
• H330-Fatal if inhaled.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
• H351-Suspected of causing cancer.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P284-¢In case of inadequate ventilation! wear respiratory protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.
• P362+P364-Take off contaminated clothing and wash it before reuse.

RUO – Research Use Only