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Thermo Scientific™ PDPH (3-(2-pyridyldithio)propionyl hydrazide)
Crosslink sulfhydryls to periodate-treated glycoprotein sugars via cleavable disulfide bonds using this short crosslinker containing pyridyldithiol and hydrazide groups.
Brand: Thermo Scientific™ 22301
Code : PN
Additional Details : CAS Number : 71-79-4 Weight : 0.80000kg
Description
Thermo Scientific™ Pierce PDPH is a short, pyridyldithiol-and-hydrazide crosslinker for reversibly conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).
Highlights:
- Pyridyldisulfide group provides a cleavable disulfide bond
- Oxidized carbohydrate-reactive hydrazide
- Reactive groups: pyridyldisulfide and hydrazide
- Reactive toward: sulfhydryl groups and carbohydrate
- Use with EDC for reactivity toward carboxyl groups
Specifications
Carbohydrate-Sulfhydryl | |
PDPH | |
No | |
Upon receipt store desiccated at 4°C. | |
Ambient | |
Chemical Labeling | |
Hydrazide, Pyridyldisulfide | |
Powder | |
DMF, DMSO | |
No |
By Thiols | |
229.32 | |
9.2 Å | |
Yes | |
Pierce™ | |
Heterobifunctional | |
Short (<10 Å) | |
50 mg | |
Standard | |
Crosslinker |
For Research Use Only. Not for use in diagnostic procedures.