Thermo Scientific™ Pierce™ Premium Grade EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)

Optimize applications where product integrity and risk minimization are paramount with this high-quality formulation of carbodiimide crosslinker.

Brand:  Thermo Scientific™ PG82073

Product Code. 15235763

Description

Optimize applications where product integrity and risk minimization are paramount with the specially characterized Thermo ScientificTM PierceTM Premium Grade EDC, our highest quality formulation of this popular carbodiimide crosslinker.

• The highest quality formulation of this popular carbodiimide crosslinker, specially characterized for applications where product integrity and risk minimization are paramount
• Compared to the standard grade product, Premium Grade EDC provides more clearly defined quality and product support
• A water-soluble carbodiimide crosslinker that activates carboxyl groups for spontaneous reaction with primary amines, enabling peptide immobilization and hapten-carrier protein conjugation
• In the presence of N-hydroxysulfosuccinimide (sulfo-NHS), EDC can be used to convert carboxyl groups to amine-reactive sulfo-NHS esters
• Store dessicated at -20°C

Features of Premium Grade EDC

• High quality – identity and purity confirmed by several tests
• Product integrity – enhanced level of testing and characterization compared to standard grade
• Lot retention – ample supply of past lots retained to ensure future process testing
• Change management – Change Control Notification (CCN) service
• Consistent manufacture – batch-specific manufacturing documentation review

Applications

• Conjugate carboxyl and amino groups among peptides and proteins
• Couple haptens to immunogenic carrier proteins
• Immobilize peptide antigens to affinity-purify antibodies
• Create NHS-activated, amine-reactive labeling compounds
• Crosslink proteins to carboxyl coated beads or surfaces
• Activate nanoparticles with amine-reactive sulfo-NHS esters

Specifications

• Chemical Reactivity: Amine-Carboxyl
• Description: EDC
• PEGylated: No
• Content And Storage: Upon receipt store desiccated at -20°C.
• Shipping Condition: Room Temperature
• Labeling Method: Chemical Labeling
• Reactive Moiety: Carbodiimide
• Form: Powder
• Solubility: Water
• Water Soluble: Yes

• Cleavable: No
• Molecular Weight (g/mol): 191.7
• Spacer Arm Length: 0.0 Å
• Cell Permeability: No
• Product Line: Pierce™
• Crosslinker Type: Heterobifunctional
• Spacer: Short (<10 Å)
• Quantity: 25 g
• Format: Standard, Single-use, Premium-grade
• Product Type: Crosslinker

Safety and Handling

Product Identifier

• Pierce Premium Grade EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H336-May cause drowsiness or dizziness.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash hands thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P405-Store locked up.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : N'-(ethylcarbonimidoyl)-N,N-dimethylpropane-1,3-diamine monohydrochloride

For Research Use Only. Not for use in diagnostic procedures.