Thermo Scientific™ Pierce™ Premium Grade EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)

Optimize applications where product integrity and risk minimization are paramount with this high-quality formulation of carbodiimide crosslinker.

Product Code	Brand	Quantity
15235763	Thermo Scientific™ PG82073	25 g
15285763	Thermo Scientific™ PG82079	1 g
15245763	Thermo Scientific™ PG82074	500 g

Description

Optimize applications where product integrity and risk minimization are paramount with the specially characterized Thermo ScientificTM PierceTM Premium Grade EDC, our highest quality formulation of this popular carbodiimide crosslinker.

• The highest quality formulation of this popular carbodiimide crosslinker, specially characterized for applications where product integrity and risk minimization are paramount
• Compared to the standard grade product, Premium Grade EDC provides more clearly defined quality and product support
• A water-soluble carbodiimide crosslinker that activates carboxyl groups for spontaneous reaction with primary amines, enabling peptide immobilization and hapten-carrier protein conjugation
• In the presence of N-hydroxysulfosuccinimide (sulfo-NHS), EDC can be used to convert carboxyl groups to amine-reactive sulfo-NHS esters
• Store dessicated at -20°C

Features of Premium Grade EDC

• High quality – identity and purity confirmed by several tests
• Product integrity – enhanced level of testing and characterization compared to standard grade
• Lot retention – ample supply of past lots retained to ensure future process testing
• Change management – Change Control Notification (CCN) service
• Consistent manufacture – batch-specific manufacturing documentation review

Applications

• Conjugate carboxyl and amino groups among peptides and proteins
• Couple haptens to immunogenic carrier proteins
• Immobilize peptide antigens to affinity-purify antibodies
• Create NHS-activated, amine-reactive labeling compounds
• Crosslink proteins to carboxyl coated beads or surfaces
• Activate nanoparticles with amine-reactive sulfo-NHS esters

Specifications

• Chemical Reactivity: Amine-Carboxyl
• Molecular Weight (g/mol): 191.7
• Spacer Arm Length: 0.0 Å
• Cell Permeability: No
• Labeling Method: Chemical Labeling
• Reactive Moiety: Carbodiimide
• Solubility: Water
• Water Soluble: Yes

• Cleavable: No
• PEGylated: No
• Content And Storage: Upon receipt store desiccated at -20°C.
• Product Line: Pierce™
• Crosslinker Type: Heterobifunctional
• Spacer: Short (<10 Å)
• Format: Standard, Single-use, Premium-grade
• Product Type: Crosslinker

Safety and Handling

Product Identifier

• Pierce Premium Grade EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H336-May cause drowsiness or dizziness.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash hands thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P405-Store locked up.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : N'-(ethylcarbonimidoyl)-N,N-dimethylpropane-1,3-diamine monohydrochloride

For Research Use Only. Not for use in diagnostic procedures.