missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organooxygen compounds
  6. Carbonyl compounds
  7. Complex Ketones
  8. Pifithrin-α hydrobromide, Tocris Bioscience™

Pifithrin-α hydrobromide, Tocris Bioscience™

Product Code. 18065102
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of cancer therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM). Cyclic analog available (Cat. No. 3843).

Chemical Identifiers

CAS 63208-82-2
Molecular Formula C16H19BrN2OS
Molecular Weight (g/mol) 367.305
InChI Key HAGVCKULCLQGRF-UHFFFAOYSA-N
Synonym pifithrin-alpha, pft-alpha, pifithrin, pifithrin-alpha hydrobromide, unii-d213b92s1y, pifithrin-, a pft, a, 2-2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl-1-p-tolylethanone hydrobromide, 2-2-imino-4,5,6,7-tetrahydrobenzo d thiazol-3 2h-yl-1-p-tolylethanone hydrobromide, 2-2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl-1-p-tolylethanone, hbr, pifithrin-alpha mi
PubChem CID 9929138
IUPAC Name 2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone;hydrobromide
SMILES CC1=CC=C(C=C1)C(=O)CN2C3=C(CCCC3)SC2=N.Br

Specifications

Quantity 10 mg
Formula Weight 367.3
Percent Purity >98%
Chemical Name or Material Pifithrin-α hydrobromide
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.