Pioglitazone hydrochloride, 98%, Thermo Scientific Chemicals

Description

 

Pioglitazone hydrochloride exhibits antiinflammatory and antiarteriosclerotic effects. It is used to prevent L-NAME-induced coronary inflammation and arteriosclerosis and to suppress increased TNF-α mRNA produced by aspirin-induced gastric mucosal injury. Pioglitazone Hydrochloride is an activator of PPAR γ. It is a PPARγ agonist and thiazolidinedione (TZD) anti-diabetic. Pioglitazone is a selective agonist of the nuclear receptor peroxisome proliferator-activated receptor γ (PPAR-γ) and to a lesser extent PPAR-α.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Pioglitazone hydrochloride exhibits antiinflammatory and antiarteriosclerotic effects. It is used to prevent L-NAME-induced coronary inflammation and arteriosclerosis and to suppress increased TNF-α mRNA produced by aspirin-ind

Specifications

• CAS: 112529-15-4
• Molecular Formula: C19H21ClN2O3S
• MDL Number: MFCD04975446
• Quantity: 250 mg
• Synonym: pioglitazone hydrochloride, pioglitazone hcl, 5-4-2-5-ethylpyridin-2-yl ethoxy benzyl thiazolidine-2,4-dione hydrochloride, pioditazone hydrochloride, 5-4-2-5-ethyl-2-pyridinyl ethoxy phenyl methyl-2,4-thiazolidinedione hydrochloride, +--5-p-2-5-ethyl-2-pyridyl ethoxy benzyl-2,4-thiazolidinedione monohydrochloride, dsstox_cid_24203, dsstox_rid_80116, dsstox_gsid_44203
• Solubility Information: Soluble in water (<1mg/ml at 25°C),DMF,methanol,ethanol (4mg/ml at 25°C),and DMSO (79mg/ml at 25°C).
• InChI Key: GHUUBYQTCDQWRA-UHFFFAOYSA-N
• SMILES: CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3.Cl
• IUPAC Name: 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride
• Molecular Weight (g/mol): 392.898
• PubChem CID: 60560
• Formula Weight: 392.9
• Percent Purity: 98%
• Chemical Name or Material: Pioglitazone hydrochloride

RUO – Research Use Only