PKM2 Mouse anti-Human, Mouse, Rat, Clone: 1C11C7, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 60268-1-IG-20UL

Product Code. 16847325

Description

PKM2, Pyruvate kinase isozymes M1/M2, has 2 isoforms. The immunogen of this antibody is M2 isoform, also called PKM2.

PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. PKM2 has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.

Specifications

• Antigen: PKM2
• Classification: Monoclonal
• Concentration: 0.53 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P11980, P14618, P52480
• Gene Symbols: PKM
• Immunogen: Peptide
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: 1C11C7
• Conjugate: Unconjugated
• Gene: PKM
• Gene Alias: CTHBP, OIP 3, OIP3, Opa interacting protein 3, p58, PK2, PK3, PKM, PKM1, PKM2, PKM2 pyruvate kinase, muscle, Pyruvate kinase 2/3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle isozyme, TCB, THBP1, Tumor M2 PK
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 18746, 25630, 5315
• Content And Storage: -20°C
• Form: Liquid